Hope in the Pipeline

Understanding Narcolepsy & Hypersomnolence Disorders Part 3

Welcome to the third part of our Hope in the Pipeline series on hypersomnolence disorders. In this episode, we dive deep into:
 
🔹 Medications used to treat narcolepsy – from older stimulants to newer, longer-lasting options
🔹 The role of antidepressants and sodium oxybate in managing symptoms like cataplexy
🔹 Key differences between narcolepsy and idiopathic hypersomnia (IH)
🔹 Current treatment options for IH and why diagnosis can be so challenging
🔹 Exciting ongoing clinical research at Preferred Research Partners, including a new potential therapy targeting narcolepsy and IH

Understanding Narcolepsy & Hypersomnolence Disorders Part 2

Welcome back to Hope in the Pipeline! In this episode, we continue our deep dive into narcolepsy, exploring:✅ What causes cataplexy (sudden loss of muscle tone)✅ How dream sleep paralysis can leak into wakefulness✅ Vivid sleep-related hallucinations and automatic behaviors✅ The detailed diagnostic process for narcolepsy, including sleep studies and genetic testing✅ How narcolepsy impacts daily life, work, and education✅ Important ADA protections and reasonable accommodations for people with narcolepsyNarcolepsy is often misunderstood, but with the right knowledge, treatment, and support, people living with it can thrive.If you found this helpful, please like, share, and subscribe for more conversations on sleep health and neurological conditions.📌 Stay tuned for Part 3 of our hypersomnolence series!

Understanding Narcolepsy & Hypersomnolence Disorders

Have you ever felt overwhelmingly sleepy even after a full night’s rest? Narcolepsy and idiopathic hypersomnia are two central disorders of hypersomnolence that affect millions worldwide — often undiagnosed.
In this episode of Hope in the Pipeline, we explore:
🧠 What narcolepsy and idiopathic hypersomnia are
🧠 Key symptoms and differences between the two
🧠 Causes, diagnosis, and treatment options
🧠 The role of the immune system in narcolepsy
🧠 How current clinical trials and research are bringing hope for better therapies
Narcolepsy is a lifelong neurological disorder caused by the loss of hypocretin (orexin), leading to uncontrollable sleepiness, cataplexy, and fragmented nighttime sleep. Idiopathic hypersomnia, on the other hand, can leave people excessively sleepy even after 10+ hours of rest. If you or someone you know struggles with unexplained sleepiness, this video will help you understand these conditions and where research is headed. 👉 Don’t forget to like, share, and subscribe to Hope in the Pipeline for more episodes on rare and underrecognized conditions.

Could Sleep Apnea Be Raising Your Blood Pressure?

Did you know that the number of blood pressure medications you take could be a sign of untreated obstructive sleep apnea?
There is a strong connection between obstructive sleep apnea (OSA) and hypertension, including the serious health risks of untreated OSA—from stroke and dementia to heart failure and even death. In this episode, Dr. Paul Wylie discusses a new clinical trial testing a promising medication designed to treat BOTH sleep apnea and high blood pressure.
✅ Learn the warning signs
✅ Understand the science
✅ Hear how you can make a difference through clinical research
#sleepapnea #hypertension #sleepmedicine #sleepstudy #obstructivesleepapnea

Menstrual Migraines Explained: New Clinical Trial Opportunity For Adults

Did you know that 12% of women experience chronic or episodic migraines, and for many, they’re tied to hormonal cycles? In this episode of Hope in the Pipeline, Dr. Paul Wylie dives into the causes, symptoms, and treatments of menstrual migraines.
🧠In this episode, you’ll learn:
What causes menstrual migraines (hint: estrogen & hormone changes)
How they differ from common migraines
Why they often respond poorly to current medications What symptoms to look for, and how to track them
Why clinical trials matter—and how YOU can get involved
 
💊 About the Clinical Trial:
Open to individuals 18 years and older 18-week study, with the option for a 1-year extension
Medication is taken just 7 days a month to help prevent migraines
Compensation provided, plus free medication during the extension period if it helps
 
🧪 This trial is testing a promising FDA-approved treatment for menstrual migraines

Understanding Insomnia: Symptoms, Treatment Options & New Clinical Trials for Kids and Adults

In this episode of Hope in the Pipeline, Dr. Paul Wylie dives deep into chronic insomnia disorder—what causes it, how it affects both children and adults, and the latest research aimed at treating it.
🧠 Learn about: The types of insomnia symptoms Differences in diagnosing pediatric vs. adult insomnia Behavioral vs. pharmacological treatments The real-life impact of chronic sleep disruption Two new clinical trials are now enrolling participants (ages 10–17 and 18–65) Why your participation could help shape the future of insomnia treatment
📚 Plus: We're giving away 3 copies of Dr. Richard Ferber’s Solving Your Child’s Sleep Problems!
 
#Insomnia #SleepMedicine #ChronicInsomnia #clinicaltrials #clinicalstudy #sleepresearch

Is It ADHD? What Parents Need to Know + Clinical Trial Info

Attention Deficit Hyperactivity Disorder (ADHD) affects millions of children — but early diagnosis and the right treatment can make a world of difference. In this episode of Hope in the Pipeline, Dr. Paul Wylie, Neuropsychiatry and Sleep Medicine Specialist, explores the symptoms, causes, and treatment options for pediatric ADHD.
We also dive into an exciting new clinical research trial for children ages 4 to 5 years and 7 months, testing a non-controlled medication already approved for older children and adults. This trial could help shape the future of ADHD treatment — and eligible families may receive a formal diagnosis and compensation for participation.
Learn how ADHD presents differently in boys and girls, the role of genetics and sleep, and why your child’s struggles might have a biological solution.
📍 Visit PreferredResearchPartners.com to learn more or apply for the study.
🔔 Don’t forget to like, share, and subscribe for more episodes on mental health breakthroughs.

Pediatric Migraines

In this episode of Hope in the Pipeline, Dr. Paul Wylie discusses pediatric migraines, their prevalence, symptoms, and treatment options. He highlights the importance of understanding how migraines affect children differently than adults and the potential for clinical trials to improve treatment outcomes. The conversation emphasizes the need for awareness and research in managing pediatric migraines effectively.

Living with Narcolepsy: What You Need to Know

In this episode of Hope in the Pipeline, Dr. Paul Wylie sheds light on narcolepsy—a complex neurological sleep disorder marked by overwhelming daytime sleepiness and sudden muscle weakness known as cataplexy. He breaks down the different types of narcolepsy, explores its symptoms, and dives into the science behind it, from genetic links to autoimmune triggers. The conversation also highlights current treatment options and promising clinical trials that aim to improve the quality of life for those living with this challenging condition.
 
#narcolepsy  #sleepdisorder #clinicaltrials #sleepmedicine

The Hidden Dangers of Shift Work: Sleep, Health & a New Treatment Study

#ShiftWork #SWSD #SleepDisorder
 
Millions of workers rely on shift work to keep essential services running, but at what cost? Dr. Paul Wylie, a Neuropsychiatry and Sleep Medicine Specialist, dives into Shift Work Sleep Disorder (SWSD)—its impact on sleep, productivity, and long-term health risks like mood disorders, diabetes, and even cancer.
Preferred Research Partners is currently enrolling participants for a 12-week clinical trial testing a medication that may improve alertness, cognitive function, and workplace safety for shift workers.
📞 501-553-9987
🌐 www.PreferredResearchPartners.com
If you or someone you know struggles with shift work-related sleep issues, watch, share, and subscribe for more sleep health insights.
#ShiftWork #SWSD #SleepDisorder #NightShift #CircadianRhythm #SleepOptimization #WorkLifeBalance #psychadelics #mentalhealth #mentalhealthawareness