Episodes

Tuesday Jul 15, 2025
Tuesday Jul 15, 2025
Did you know that 12% of women experience chronic or episodic migraines, and for many, they’re tied to hormonal cycles? In this episode of Hope in the Pipeline, Dr. Paul Wylie dives into the causes, symptoms, and treatments of menstrual migraines.
🧠In this episode, you’ll learn:
What causes menstrual migraines (hint: estrogen & hormone changes)
How they differ from common migraines
Why they often respond poorly to current medications What symptoms to look for, and how to track them
Why clinical trials matter—and how YOU can get involved
💊 About the Clinical Trial:
Open to individuals 18 years and older 18-week study, with the option for a 1-year extension
Medication is taken just 7 days a month to help prevent migraines
Compensation provided, plus free medication during the extension period if it helps
🧪 This trial is testing a promising FDA-approved treatment for menstrual migraines

Friday Jul 11, 2025
Friday Jul 11, 2025
In this episode of Hope in the Pipeline, Dr. Paul Wylie dives deep into chronic insomnia disorder—what causes it, how it affects both children and adults, and the latest research aimed at treating it.
🧠 Learn about: The types of insomnia symptoms Differences in diagnosing pediatric vs. adult insomnia Behavioral vs. pharmacological treatments The real-life impact of chronic sleep disruption Two new clinical trials are now enrolling participants (ages 10–17 and 18–65) Why your participation could help shape the future of insomnia treatment
📚 Plus: We're giving away 3 copies of Dr. Richard Ferber’s Solving Your Child’s Sleep Problems!
#Insomnia #SleepMedicine #ChronicInsomnia #clinicaltrials #clinicalstudy #sleepresearch

Wednesday Jun 18, 2025
Wednesday Jun 18, 2025
Attention Deficit Hyperactivity Disorder (ADHD) affects millions of children — but early diagnosis and the right treatment can make a world of difference. In this episode of Hope in the Pipeline, Dr. Paul Wylie, Neuropsychiatry and Sleep Medicine Specialist, explores the symptoms, causes, and treatment options for pediatric ADHD.
We also dive into an exciting new clinical research trial for children ages 4 to 5 years and 7 months, testing a non-controlled medication already approved for older children and adults. This trial could help shape the future of ADHD treatment — and eligible families may receive a formal diagnosis and compensation for participation.
Learn how ADHD presents differently in boys and girls, the role of genetics and sleep, and why your child’s struggles might have a biological solution.
📍 Visit PreferredResearchPartners.com to learn more or apply for the study.
🔔 Don’t forget to like, share, and subscribe for more episodes on mental health breakthroughs.

Tuesday Jun 03, 2025
Tuesday Jun 03, 2025
In this episode of Hope in the Pipeline, Dr. Paul Wylie discusses pediatric migraines, their prevalence, symptoms, and treatment options. He highlights the importance of understanding how migraines affect children differently than adults and the potential for clinical trials to improve treatment outcomes. The conversation emphasizes the need for awareness and research in managing pediatric migraines effectively.

Friday May 16, 2025
Friday May 16, 2025
In this episode of Hope in the Pipeline, Dr. Paul Wylie sheds light on narcolepsy—a complex neurological sleep disorder marked by overwhelming daytime sleepiness and sudden muscle weakness known as cataplexy. He breaks down the different types of narcolepsy, explores its symptoms, and dives into the science behind it, from genetic links to autoimmune triggers. The conversation also highlights current treatment options and promising clinical trials that aim to improve the quality of life for those living with this challenging condition.
#narcolepsy #sleepdisorder #clinicaltrials #sleepmedicine

Monday Mar 31, 2025
Monday Mar 31, 2025
#ShiftWork #SWSD #SleepDisorder
Millions of workers rely on shift work to keep essential services running, but at what cost? Dr. Paul Wylie, a Neuropsychiatry and Sleep Medicine Specialist, dives into Shift Work Sleep Disorder (SWSD)—its impact on sleep, productivity, and long-term health risks like mood disorders, diabetes, and even cancer.
Preferred Research Partners is currently enrolling participants for a 12-week clinical trial testing a medication that may improve alertness, cognitive function, and workplace safety for shift workers.
📞 501-553-9987
🌐 www.PreferredResearchPartners.com
If you or someone you know struggles with shift work-related sleep issues, watch, share, and subscribe for more sleep health insights.
#ShiftWork #SWSD #SleepDisorder #NightShift #CircadianRhythm #SleepOptimization #WorkLifeBalance #psychadelics #mentalhealth #mentalhealthawareness

Thursday Mar 13, 2025
Thursday Mar 13, 2025
An in-depth exploration of social anxiety disorder and generalized anxiety disorder, discussing their symptoms, prevalence, and the impact they have on individuals' lives. Dr. Paul Wylie shares insights into the causes, treatment options, and the importance of clinical trials in advancing mental health care. The discussion highlights the innovative treatments being tested to improve the quality of life for those affected.

Thursday Mar 13, 2025
Thursday Mar 13, 2025
This conversation explores the emerging field of psychedelic research in mental health, focusing on the potential of psychedelic medications to treat mood disorders. Dr. Paul Wylie, a neuropsychiatrist, discusses the historical context of mental health treatments, the evolution of psychedelics in therapy, and the mechanisms by which they may promote neuroplasticity and improve mental health outcomes. Katie Walker, a therapist and participant in a clinical trial, shares her personal experiences and insights into the therapeutic process, emphasizing the importance of safety and integration in treatment. This conversation delves into the evolving landscape of psychedelic therapy, focusing on the therapeutic toolbox available to clients, the future of psychedelic treatments, safety measures in clinical trials, and the financial aspects of participation in these studies. The speakers emphasize the importance of collaboration between therapists and clinical researchers to optimize the therapeutic experience while ensuring participant safety and rights.